An away team is captured by the Vidiians, who extract Torres' Klingon DNA in an effort to find a cure for a disease ravaging their people - but the process turns Torres into two people, one fully Klingon, one fully human.
An alien doctor responsible for a weapon used against the Talaxians believes Neelix may be infected with a fatal disease as an aftereffect of exposure to it.
The ship's systems mysteriously begin to malfunction; Tuvok takes on the task of training Maquis crew members in Star Fleet discipline.
The crew discovers Amelia Earhart among eight humans preserved by cryogenics after they follow a distress signal to an alien planet.
After a Kazon attack, the Doctor must leave sickbay to assess damage to the ship, and comes to suspect that he's real and everything else is a hologram.